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Senescent cells undergo major morphological and metabolic changes when at the end of their lifespan. 

Cells use a variety of programmed cell death (PCD) mechanisms to maintain homeostasis, including apoptosis, necroptosis, and pyroptosis.  

Scientists employ cutting edge tools and techniques to create artificial organs for research and disease therapeutics.

Deconstructing concepts, approaches, and data analysis in proteomics workflows.  

Researchers employ peripheral blood mononuclear cells (PBMCs) in clinical and academic applications related to the immune system and regenerative medicine.

Neurons transmit information through the body via chemical signals and electrical impulses.

Scientists develop cancer nutrition guidelines based on research examining how dietary patterns affect cancer risk and prevention.

High throughput sequencing is a versatile technology that revolutionized the field of genetics.

Microbes communicate with quorum sensing to coordinate their behavior in response to how many neighbors they have.

A new frontier in repairing organ damage

Andrew Pospisilik explores the epigenetic changes that give organisms the plasticity to change in response to their environments.

Scientists study pluripotent stems cells to understand early development and how to use them in regenerative medicine, disease modeling, and drug discovery.

Prior to DNA methylation sequencing, researchers treat their samples with sodium bisulfite to distinguish methylated cytosine from unmethylated cytosine.

Scientists study human health in vivo with modified mice that molecularly mimic human biology.

Miniaturized, in vitro versions of organs provide insights into disease and development.

A unique approach to antibody production that exposes antibody candidates to nucleosomes is revolutionizing best practices.

Identifying novel biomarkers of Parkinson’s disease enables early diagnosis and treatment monitoring.

Cancer immunotherapy targets the tumor microenvironment, blocking the molecular pathways that tumors exploit to prevent immune cell activity.

Guidelines and built-in safeguards ensure the reproducibility of flow cytometry data.