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Probing “Selfish” Centromeres Unveils an Evolutionary Arms Race

Michael Lampson, PhD | Apr 3, 2023 | 10 min read

A more complete understanding of nonrandom segregation will shed light on how speciation occurs.

Infographic depicting one way centromeres can "cheat" during meiosis

Infographic: How “Selfish” Centromeres Alter Inheritance

Michael Lampson, PhD | Apr 3, 2023 | 2 min read

Research on so-called selfish genetic loci is providing scientists with greater insight into the biology of chromosome segregation and inheritance.

Improve qPCR Efficiency and Reproducibility

The Components of Effective qPCR

Bio-Rad | 1 min read

Putting the pieces together for molecular diagnostics and infectious disease research

Artist’s rendition of red SARS-CoV-2 coronaviruses floating near blue strands of DNA.

COVID-19 Infections May Reshape Genetic Landscape

Holly Barker, PhD | Mar 30, 2023 | 3 min read

SARS-CoV-2 infection triggers structural changes in the host cell’s DNA, which provide a molecular explanation for long COVID, a new study suggests.

electron micrograph of grey cancer cell, with two red T cells stuck to the side

Translation of “Jumping Genes” Creates Cancer Therapy Targets

Natalia Mesa, PhD | Mar 29, 2023 | 4 min read

Researchers find many tumor-specific antigens form when cancer genes and transposable elements link up.

Genomes Across the Tree of Life

The Scientist’s Creative Services Team | 2 min read

Researchers turn to unique eukaryotes to better understand how DNA is organized in 3D space.

A normal human liver organoid (left) stained with blue and red next to a fatty liver organoid (right) with lipid droplets stained yellow.

Working Together to Battle Fatty Liver Disorders

Niki Spahich, PhD | Mar 24, 2023 | 6 min read

Benedetta Artegiani and Delilah Hendriks are forming a joint laboratory group to understand disease mechanisms and treatments through organoid models.

‘Godfather of Genetic Engineering’ Paul Berg Dies at 96

Lisa Winter | Mar 23, 2023 | 3 min read

Berg was awarded one-half of the Nobel Prize in Chemistry in 1980 for his work with recombinant DNA technology.

Learn how to efficiently and gently prepare samples for NGS and beyond

How to Improve Yield and Reproducibility in Different -Omics Applications

Covaris | 1 min read

Extracting nucleic acids and proteins gently from samples increases experimental success.

Copepod (Zooplankton) are a group of small crustaceans found in the marine and freshwater habitat.

Combining Climate Stressors Leads to Unique Changes in the Genome

Jennifer Zieba, PhD | Mar 20, 2023 | 3 min read

Researchers found that copepod genomes adapt in distinct ways when simultaneously exposed to multiple environmental conditions.

Healthcare and medicine, Doctor touch and diagnose a virtual Human Lungs with Covid-19 or coronavirus spread inside on modern interface screen on laboratory, Innovation and Medical technology.

Uncovering Rare Disease Genetic Pathways with Global Biobanks

Deanna MacNeil, PhD | Mar 20, 2023 | 3 min read

Researchers discover new idiopathic pulmonary fibrosis risk factors with multi-ancestry analyses that increase representation of understudied populations.

Context Is Key: Unlocking Tissue Complexity with Spatial Biology

Deanna MacNeil, PhD | 4 min read

Scientists combine spatially resolved imaging analyses with cutting edge single cell techniques for greater insight into fundamental and disease relevant pathways.

Hormone Therapy Triggers Male Gene Patterns in Transgender Men’s Cells

Holly Barker, PhD | Mar 15, 2023 | 3 min read

A study deepens the scientific understanding of how androgens influence breast tissue, which may offer clues to treating breast cancer.

Fluorescent images of red cells showing high and low levels of infection in green

Parasite Drove Natural Selection in Amazonian Indigenous Groups

Natalia Mesa, PhD | Mar 13, 2023 | 4 min read

The findings could help researchers understand why some individuals are more vulnerable to deadly Chagas disease.

Relieving the Pipetting Toll for Better Results

The Scientist’s Creative Services Team and BRANDTECH Scientific | 3 min read

Scientists use an automated liquid handling station to ensure consistency across a range of experiments.

Artistic rendition of droplet DNA amplification

Finally, Scientists Sequence Single Cells with Long-Read Technology

Holly Barker, PhD | Mar 8, 2023 | 4 min read

By combining two innovative approaches, researchers can now sequence the full spectrum of mutational differences between individual cells’ genomes.

Michael Green smiling at the camera in front of a shelf in the lab

Molecular Biologist Michael Green Dies at 69

Lisa Winter | Mar 7, 2023 | 2 min read

Beyond his achievements in academia, he also cofounded three pharmaceutical companies and filed 15 patents related to cancer therapeutics.

A Way with Words: Using Genomics to Dispel Stuttering Myths

The Scientist’s Creative Services Team | 1 min read

Filling in the gaps about the genetic risk factors of stuttering may help scientists shatter stigmas and discover new therapies.

Mutational Signature Indicates Risk of Kidney Cancer Recurrence

Holly Barker, PhD | Mar 1, 2023 | 2 min read

DNA sequencing can identify mutations that predict recurrence of renal cell carcinoma and may help low-risk patients avoid unnecessary treatment, a study finds.