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Stress Increases Biological Age, But Recovery Can Revert It

Alejandra Manjarrez, PhD | Apr 21, 2023 | 2 min read

A new study relying on DNA methylation clocks suggests that the biological age of mouse and human cells can fluctuate in response to stressful events.

Image shows photorhabdus virulence cassettes (green) binding to insect cells (blue) prior to injection of payload proteins.

Engineered Bacterial “Syringes” Can Deliver Drugs Into Human Cells

Rohini Subrahmanyam, PhD | Apr 20, 2023 | 4 min read

Researchers repurpose tiny bacterial injection systems to specifically inject a wide variety of proteins into human cells and living mice.

Important Players for a Successful PCR

The Scientist’s Creative Services Team and MilliporeSigma | 1 min read

Learn about other PCR components—beyond the polymerase—that are essential for optimal results.

New Brain Network Connecting Mind and Body Discovered

Natalia Mesa, PhD | Apr 19, 2023 | 4 min read

A new brain network responsible for complex movements may upend what we know about neural maps in primary motor areas

Rare Autism-Linked Mutation Starves Growing Neurons of Essential Nutrients

Lauren Schenkman, Spectrum | Apr 18, 2023 | 4 min read

The mutation prevents certain amino acids from entering neurons, causing the cells to die early in development.

Time for a Change: Evidence-Based Approaches for the Biological Safety Assessment of Medical Devices

The Scientist’s Creative Services Team | 1 min read

In this webinar, Ron Brown discusses the problems with current medical device biological safety assessment approaches and suggests that evidence-based strategies could be the solution.

Green and brown illustration of cancer cells in front of a peach and yellow background.

Bacterial Tractor Beams Bring Radiation to Tumors

Rachael Moeller Gorman | Apr 17, 2023 | 3 min read

Colonizing tumors with engineered bacteria may allow researchers to target sites currently inaccessible to radionuclide therapy.

Immune Molecule Alters Cellular Makeup of Human Brain Organoids

Charles Q. Choi, Spectrum | Apr 17, 2023 | 4 min read

The changes may help explain the link between maternal infection and autism, though more research is needed.

3D rendered image of multiple antibody-drug conjugate next generation antibodies.

Advances in Antibody Therapeutics

Elina Kadriu | 4 min read

Scientists engineer therapeutic antibodies with improved stability and efficacy.

Hibernating Bears Provide Clue to Preventing Serious Clots in Humans

Natalia Mesa, PhD | Apr 13, 2023 | 3 min read

Low levels of the clotting factor HSP47 protect the sleeping giants from blood clots, and the same may be possible for humans and other mammals.

Bladder epithelial tissue, where cell junctions are shown in green and nuclei in blue. This was grown in vitro from cells taken from mice with chronic cystitis.

Bladder ‘Memory’ Influences Urinary Tract Infection Recurrence in Mice

Alejandra Manjarrez, PhD | Apr 12, 2023 | 3 min read

Urinary tract infections leave permanent epigenetic marks in the mouse bladder epithelium, reprogramming its response to subsequent infections, a study finds.