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One hand holding the other, depicting pain in the joints
A Bacterial Culprit for Rheumatoid Arthritis
Scientists identified a species of Subdoligranulum that may drive disease.
A Bacterial Culprit for Rheumatoid Arthritis
A Bacterial Culprit for Rheumatoid Arthritis

Scientists identified a species of Subdoligranulum that may drive disease.

Scientists identified a species of Subdoligranulum that may drive disease.

microbiome

Two pink-colored, rod-shaped bacteria interacting with a blue-colored human cell
Gut Bacterium Linked to Depression in Premenopause
Alejandra Manjarrez, PhD | Mar 17, 2023 | 2 min read
The opportunistic pathogen Klebsiella aerogenes degrades estradiol and induces depressive-like behavior in mice, a study finds.
T regulatory cell in red sandwiching an antigen presenting cell in blue
Gut Bacteria Help T Cells Heal Muscle: Study
Natalia Mesa, PhD | Mar 14, 2023 | 4 min read
Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.
Discover the microbiome’s role in diabetes 
A Question of Balance: How the Gut Microbiome Influences Diabetes
The Scientist’s Creative Services Team | 1 min read
The presence of beneficial or detrimental microbes pulls the host toward health or disease.
Artist's rendering of rod-shaped bacteria
Gut Microbiomes Offer Insights into Chronic Fatigue Syndrome
Shafaq Zia | Feb 21, 2023 | 2 min read
Levels of health-promoting gut bacteria are linked with severity of fatigue symptoms, a study finds.
a white mouse sits on a blue exercise wheel, looking out onto the shavings below
Mice With a Healthy Gut Microbiome Are More Motivated to Exercise
Katherine Irving | Dec 16, 2022 | 4 min read
A neural pathway between the gut and the brain led to the release of dopamine when the mice ran on a wheel or treadmill, but only in the presence of a robust microbiome. 
VAI
One Sequence, Many Variations
Van Andel Institute | 5 min read
Andrew Pospisilik explores the epigenetic changes that give organisms the plasticity to change in response to their environments.
Alma Dal Co wears a blue shirt and red necklace and uses a pointer to examine a component of a laboratory machine. 
Microbial Ecologist Alma Dal Co Dies in Diving Accident
Katherine Irving | Nov 21, 2022 | 3 min read
At 33, Dal Co had already founded her own microbial ecology lab at the University of Lausanne in Switzerland.
Illustration showing immunology during pregnancy
Infographic: How Immunology Can Influence Pregnancy Outcomes
Tobias R. Kollmann, Arnaud Marchant, and Sing Sing Way | Nov 14, 2022 | 3 min read
Pregnancy-induced changes in the immune system are key to a successful birth. Understanding those changes could allow researchers to protect both mother and child.
VAI
Exposed: Environmental Echoes in Health - A Special Podcast Series
The Scientist’s Creative Services Team and Van Andel Institute | 2 min read
Epigenetic experts discuss how environment and diet leave lasting impressions on the human genome.
Illustration of pregnancy and the immune system
Modulating Immunity to Improve Pregnancy Outcomes
Tobias R. Kollmann, Arnaud Marchant, and Sing Sing Way | Nov 14, 2022 | 10+ min read
Aberrant immune activation, the main cause of prematurity and stillbirths, could be preventable through interventions such as maternal vaccination. 
a small black mouse sits next to an obese black mouse on a white background
Obesity Protects Against Genital Herpes in Mice, Study Finds
Katherine Irving | Nov 11, 2022 | 3 min read
A high-fat diet induced changes to the animals’ vaginal microbiomes that boosted survival after exposure to the virus.
A nude (hairless) mouse, typically used in biomedical and drug discovery research methods that rely on immunodeficient mouse strains.
Brush Up: Humanized Mice: More than the Sum of Their Parts
Deanna MacNeil, PhD | 5 min read
Scientists study human health in vivo with modified mice that molecularly mimic human biology.
Matthieu Groussin sits with three other people on stools in front of a low table, on which there are several bowls of food. Another person stands above Groussin spooning something into a bowl.
Q&A: Gathering Diverse Microbiome Samples
Katherine Irving | Nov 3, 2022 | 8 min read
Cofounders of a microbiome biobank speak with The Scientist about their new partnership with nonprofit OpenBiome and how to ethically work with donors.
Illustration of green fluorescent bacterial cells.
Cocaine Use Creates Feedback Loop with Gut Bacteria: Mouse Study
Alejandra Manjarrez, PhD | Nov 1, 2022 | 3 min read
A jolt of norepinephrine in the mouse gut facilitates colonization by certain microbes, which in turn deplete glycine, enhancing cocaine-induced behaviors.
Leveraging the Microbiome to Break Down Tumor Resistance
Leveraging the Microbiome to Break Down Tumor Resistance
The Scientist’s Creative Services Team and PerkinElmer | 1 min read
Mat Robinson and Mark Tangney discuss how enhancing the efficacy of immune checkpoint inhibitors improves patient outcomes.
Orange colony of bacteria on red medium
Skin Bacteria May Trigger Lupus: Mouse Study
Natalia Mesa, PhD | Oct 28, 2022 | 3 min read
Staphylococcus aureus appears to be the culprit.
Three white mice
High-Fat Diet in Mice Affects Social Behavior Across Generations
Sophie Fessl, PhD | Oct 27, 2022 | 4 min read
Pups born to mice whose mothers had been fed a high-fat diet showed social deficits, a study shows. 
The Gripper Tower lab scene epMotion
Automating NGS Library Prep
The Scientist’s Creative Services Team and Eppendorf | 3 min read
Liquid handlers specialized for next-generation sequencing (NGS) automate nucleic acid extraction and library preparation from microbiome samples.
an&nbsp;<em>Aedes aegypti&nbsp;</em>mosquito, black with white dots and stripes on its joints and body, sitting on a person&#39;s skin and feeding.&nbsp;
Smelly Skin Compounds Draw Mosquitoes to Some People More than Others
Katherine Irving | Oct 19, 2022 | 3 min read
People with more carboxylic acids in their body odor are more attractive to mosquitoes, a study finds.
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