gene editing

In both the laboratory and clinic, scientists harness viral genetic transfer capabilities to develop gene therapies that modulate cellular function.

Mycoplasma pneumoniae with pathogenic genes replaced by biofilm-degrading ones enhance survival in a mouse model of ventilator-associated pneumonia.

A biotech startup called Tessera Therapeutics has made a splash with its claims about the trademarked technology. Is the excitement justified?

Researchers say structures made of the cells could potentially be used to clean up uranium from oceans, heal wounds, and more.

Staphylococcus aureus appears to be the culprit.

The findings will likely help elucidate the effects of chromosome fusions, which can cause disease but have also contributed to evolution.

The biotech company Verve Therapeutics launched the study with the aim of using base editing to treat a genetic condition that causes high cholesterol and increases a person's risk of developing cardiovascular disease.

A study finds that CRISPR-Nickase, which changes just one allele of a given gene, improves gene editing efficiency compared with CRISPR-Cas9.

This month marks ten years since CRISPR-Cas9 was repurposed as a gene editing system, so we’re looking back at what has been accomplished in a decade of CRISPR editing.

A new technique goes beyond CRISPR and writes two complementary strands of DNA directly into the genome.

The approach, called GRAND, uses a second guide RNA to write complementary strands of DNA in targeted genomic locations, resulting in efficient insertions that can be hundreds of base pairs long.

A new method has allowed researchers to conduct the first gene knock-out and knock-in edits on cockroaches and may extend to many other insects.

A CRISPR-based system that reverses epigenetic changes caused by adolescent binge drinking reduces adult addiction-like behaviors in rats, a study finds, suggesting that an epigenomic approach could someday help treat people with alcohol use disorder.