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physiology

Artist’s rendition of the molecular structure of a ribosome (blue and purple) as it produces a polypeptide chain (red) from an mRNA template (orange and gray), with tRNA molecules (dark purple) shuttling amino acids.
Specialized Sperm Ribosomes Are Key to Male Fertility in Mice
Dan Robitzski | Dec 15, 2022 | 4 min read
A previously unknown kind of ribosome is responsible for folding sperm proteins, which decay before fertilization if prepared by other ribosomes.
A grayscale tomography image of snake tissue
Snakes Have Clitorises After All, Study Finds
Natalia Mesa, PhD | Dec 13, 2022 | 4 min read
Researchers visualize the snake clitoris in detail for the first time, finding evidence that the organ may be evolutionarily important for snake sex.
Developing Aptamer Biosensor Technology for Diagnostics and Therapeutics
Expanding the Available Target Range for New Drugs and Diagnostics with Aptamers
The Scientist’s Creative Services Team and aptamer Group | 1 min read
In this roundtable discussion, an expert panel will discuss how the latest applications of aptamer technology are enabling innovation across the life sciences by replacing antibodies.
close-up photo of fruit fly on white background
Scientists ID Heart-Damaging SARS-CoV-2 Protein
Grace van Deelen | Nov 22, 2022 | 3 min read
In flies and mice, a viral protein increases the rate of energy use by heart cells. But it’s not yet clear if the finding applies to humans.
Turkey, mashed potatoes, stuffing, pumpkin pie and sides on a table
The Smell of Food Affects Metabolism in Fasting Mice
Shafaq Zia | Nov 18, 2022 | 3 min read
The odor prompted the animals’ fat cells to release lipids into circulation.
Large-Scale Proteomics Drives Disease Research
Driving Disease Research and Therapeutics with Large-Scale Proteomics
The Scientist’s Creative Services Team and SomaLogic | 1 min read
Explore how technology enables large-scale proteomics for biomarker discovery and clinical application.
A mouse in front of an open sack of grain.
Mice Fed a Highly Processed Diet Are More Susceptible to the Flu
Alejandra Manjarrez, PhD | Nov 18, 2022 | 3 min read
It’s not clear why grain-fed mice are better able to recover after infection, but a study’s findings suggest food type may skew the results of animal studies.
A nine-banded armadillo walking on dry grass.
Leprosy Bacterium Rejuvenates Armadillos’ Livers
Alejandra Manjarrez, PhD | Nov 15, 2022 | 4 min read
Mycobacterium leprae appeared to reprogram the animals’ livers to a state partially resembling early development, resulting in healthy organ growth.
Enzymes Cutting Extracellular Matrix
An Introduction to Enzymes
The Scientist’s Creative Services Team | 1 min read
Discover how enzymes work and why they're an integral part of scientific laboratories.
Illustration showing immunology during pregnancy
Infographic: How Immunology Can Influence Pregnancy Outcomes
Tobias R. Kollmann, Arnaud Marchant, and Sing Sing Way | Nov 14, 2022 | 3 min read
Pregnancy-induced changes in the immune system are key to a successful birth. Understanding those changes could allow researchers to protect both mother and child.
Illustration of pregnancy and the immune system
Modulating Immunity to Improve Pregnancy Outcomes
Tobias R. Kollmann, Arnaud Marchant, and Sing Sing Way | Nov 14, 2022 | 10+ min read
Aberrant immune activation, the main cause of prematurity and stillbirths, could be preventable through interventions such as maternal vaccination. 
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Metabolomic Links Between Environmental Exposures and Human Health
The Scientist’s Creative Services Team | 1 min read
Experts discuss how untargeted metabolomic studies connect environmental factors with human disease.
An international team of scientists used sensitive instruments to show that oil from human skin reacts with ozone to generate potent, free radicals. These chemicals can further react with most organic compounds present in the indoor environment to produce dangerous pollutants. 
Caught on Camera
The Scientist Staff | Nov 14, 2022 | 3 min read
See some of the coolest images recently featured by The Scientist
fluorescently labeled microscopy cross-section of bone
Cancer Cells in Mice May Hitch a Ride with Bone-Healing Stem Cells
Andy Carstens | Nov 7, 2022 | 4 min read
Researchers have long observed a connection between bone metastasis and remodeling, which might be due to a close connection between the two cell types. 
Spatial Biology in Physiology and Pathology
Spatial Biology in Physiology and Pathology
The Scientist’s Creative Services Team | 1 min read
Elana Fertig and Sanjay Srivatsan discuss the importance of the spatial dimension for biological systems research.
network of intestinal blood vessels
Science Snapshot: No Guts, No Glory
Lisa Winter | Nov 1, 2022 | 1 min read
This image took 3rd place at the 2022 Nikon Small World Photomicrography Competition.
Breast tissue shown in pink and yellow
Science Snapshot: Milking It
Lisa Winter | Oct 31, 2022 | 1 min read
This image took 2nd place at the 2022 Nikon Small World Photomicrography Competition.
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Demystifying the Black Box
The Scientist’s Creative Services Team and Tecan | 1 min read
One sophisticated laboratory tool detects absorbance, fluorescence, FRET, luminescence, live cells, and more, facilitating a wide variety of experimental findings.
Three white mice
High-Fat Diet in Mice Affects Social Behavior Across Generations
Sophie Fessl, PhD | Oct 27, 2022 | 4 min read
Pups born to mice whose mothers had been fed a high-fat diet showed social deficits, a study shows. 
A portrait shot of Beryl Benacerraf, who wears a black shirt and gold necklace and smiles into the camera, on a bluish gray background.
Obstetrics “Giant” Beryl Benacerraf Dies at 73
Katherine Irving | Oct 26, 2022 | 2 min read
Benacerraf pioneered the use of ultrasound to diagnose fetal syndromes.
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