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Electron micrograph of cancer cell with T cells stuck to the side, colored in red
Translation of “Jumping Genes” Creates Cancer Therapy Targets
Researchers find many tumor-specific antigens form when cancer genes and transposable elements link up.
Translation of “Jumping Genes” Creates Cancer Therapy Targets
Translation of “Jumping Genes” Creates Cancer Therapy Targets

Researchers find many tumor-specific antigens form when cancer genes and transposable elements link up.

Researchers find many tumor-specific antigens form when cancer genes and transposable elements link up.

T cell

T regulatory cell in red sandwiching an antigen presenting cell in blue
Gut Bacteria Help T Cells Heal Muscle: Study
Natalia Mesa, PhD | Mar 14, 2023 | 4 min read
Regulatory T cells in the colon travel to muscles to promote wound healing in mice, raising questions about how antibiotics may impact injury recovery.
Red T cell
Jumping Genes Put a Target on Cancerous Cells
Natalia Mesa, PhD | Feb 14, 2023 | 4 min read
Two studies find that tumor-specific antigens are often peptides that result from a splicing event between exons and transposable elements.
TSS
Immune Cells and ALS: A Balance Between Life and Death
The Scientist’s Creative Services Team | 1 min read
Understanding the role of immune cells in neurodegeneration may help scientists develop new diagnostic, prognostic, and treatment tools.
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist Staff | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
Microscopy image of the cnidarian <em>Hydractinia symbiolongicarpus&nbsp;</em>with cell nuclei stained blue and oocytes stained yellow
Ancient Immunoglobulin Genes Help Cnidarians Decide to Fight or Fuse
Sophie Fessl, PhD | Oct 11, 2022 | 4 min read
Immunoglobulin genes might have evolved much earlier than previously expected, perhaps even in the common ancestor of Cnidarians and Bilateria, a study suggests.
Developing Effective Cell Therapies for Challenging Cancer Types&nbsp;
Developing Effective Cell Therapies for Challenging Cancer Types
The Scientist’s Creative Services Team | 1 min read
In this webinar, Sandhya Sharma will discuss how to enrich for antigen-specific T-cells to treat virus-associated malignancies.
A full blood sample vial lying on top of a piece of paper that reads &ldquo;Acute lymphoblastic leukemia&rdquo;.
Targeting Leukemia with T Cells That Avoid Self-Destruction
Deanna MacNeil, PhD | Sep 26, 2022 | 3 min read
Researchers found that naturally-occurring CD7-negative T cells avoid self-destruction and are good effectors in CAR T therapy for T cell blood cancers.
3D rendered images of three T cell
T Cells Ward Off Aging with Help from Their Friends
Natalia Mesa, PhD | Sep 16, 2022 | 5 min read
Immune cells deliver packages of telomeres to T cells, helping them retain their virus-fighting function over time, research suggests.
Overcoming T Cell Therapy Barriers with Engineered Proteins
Overcoming T Cell Therapy Barriers with Engineered Proteins
The Scientist’s Creative Services Team | 1 min read
Shannon Oda will discuss how to develop novel engineered fusion proteins to improve T cell therapies against hematological and solid tumors.
Illustration showing rod-shaped Mycobacterium tuberculosis bacteria in the lungs of a person with tuberculosis
Delayed T cell Response Allows Tuberculosis to Gain Foothold in Monkeys
Anna Napolitano, PhD | Jun 1, 2022 | 5 min read
The results could help guide the design of new vaccines for the disease.
Microscopic image of nerves in the eye, a pathogen, and t cells
Science Snapshot: Eye Immunity
Lisa Winter | May 26, 2022 | 1 min read
Researchers find that tissue-resident memory T cells in the corneas of mice engender a lasting immune response.
The Epigenetic Landscape During T Cell Exhaustion
The Epigenetic Landscape During T Cell Exhaustion
The Scientist’s Creative Services Team and 10x Genomics | 1 min read
In this webinar, E. John Wherry and Debattama Sen will discuss how epigenetic scarring of exhausted T cells influences chronic infections.
Tiliqua rugosa, sleepy lizard, on reddish soil in western Australia
Researchers Probe Genetics Behind a Lizard’s Odd Immune System
Hannah Thomasy, PhD, Drug Discovery News | May 10, 2022 | 4 min read
Deletions in the sleepy lizard genome leave it without an important type of T cells found in most other vertebrates.
illustration of thymus in white on a green background
New Mechanism for Virus-Triggered Autoimmunity Uncovered
Sophie Fessl, PhD | Mar 11, 2022 | 4 min read
Roseolovirus infection disrupts how the body trains immune cells not to attack it, a mouse study shows.
The Many Facets of T Cell Exhaustion
The Many Facets of T Cell Exhaustion
The Scientist Creative Services Team in Collaboration with IsoPlexis | 1 min read
In this webinar, Abhishek Garg will discuss using functional proteomics and multi-omics approaches to explore exhausted/dysfunctional T cell states in various cancers.
illustration of inside of human chest with highlighted gland between the lungs
Genetically Altered Mice Harness Benefits of Calorie Restriction  
Sophie Fessl, PhD | Feb 11, 2022 | 4 min read
A study identifies a gene that appears to be partially responsible for the health effects of a limited diet.
Salmonella (pink) invading a human epithelial cell (yellow)
Modified Salmonella Revs Immune Response, Combats Tumors in Mice
Natalia Mesa, PhD | Feb 3, 2022 | 5 min read
When coated with positively charged particles, the bacteria shuttled antigens out of tumors and activated the immune system, a study finds.
A Spotlight on T Cell Exhaustion
A Spotlight on T Cell Exhaustion
The Scientist’s Creative Services Team | 1 min read
Mary Philip and Benjamin Youngblood discuss how T cell exhaustion affects cancer progression and immunotherapy efficacy.
knitted pink heart with a mended hole
CAR T Cells Mend Broken Mouse Hearts
Sophie Fessl, PhD | Jan 6, 2022 | 4 min read
Specialized immune cells generated in vivo reduce cardiac scar tissue in mice, a new study shows.
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