synthetic biology

Scientists engineered human pluripotent stem cells with synthetic gene circuits to control differentiation without human input.

Researchers engineer a protease-mediated post-translational path faster than gene switches for processes that need to happen quickly, such as insulin release.

Two studies in mice now show that researchers can control when and where CAR T cells are active, potentially overcoming previous hurdles for CAR T–based treatments.

Researchers say structures made of the cells could potentially be used to clean up uranium from oceans, heal wounds, and more.

A team proposes that the addition of a small accessory subunit to the carbon-fixing enzyme was key to improving its catalytic properties and specificity to CO₂.

His research paved the way for the development of synthetic insulin to treat diabetes.

Scientists added a gene circuit that senses and neutralizes proinflammatory ATP to yeast, taking another step towards precision medicine.

Synthetic biologists introduced an engineered microbe that may lead to new treatment options for phenylketonuria.

A device smaller than two stacked decks of cards can reliably detect and discriminate between SARS-CoV-2 variants in spit in less than an hour with results that glow.

Pairing CARs with a synthetic receptor makes T cells more lethal tumor killers.

Researchers are adapting CRISPR, synthetic biology, and other creative approaches to detect SARS-CoV-2 nucleic acids outside of the lab or doctors’ offices, in the hopes of making diagnostics more affordable and accessible.

Junior faculty in particular may lose ground as undergrad students remain barred from university labs.

Here’s how my group put our research on pause and how we’ve continued our work from home.