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Bladder epithelial tissue, where cell junctions are shown in green and nuclei in blue. This was grown in vitro from cells taken from mice with chronic cystitis.
Bladder ‘Memory’ Influences Urinary Tract Infection Recurrence in Mice
Urinary tract infections leave permanent epigenetic marks in the mouse bladder epithelium, reprogramming its response to subsequent infections, a study finds.
Bladder ‘Memory’ Influences Urinary Tract Infection Recurrence in Mice
Bladder ‘Memory’ Influences Urinary Tract Infection Recurrence in Mice

Urinary tract infections leave permanent epigenetic marks in the mouse bladder epithelium, reprogramming its response to subsequent infections, a study finds.

Urinary tract infections leave permanent epigenetic marks in the mouse bladder epithelium, reprogramming its response to subsequent infections, a study finds.

stem cells

A robotic hand adding a piece of DNA to an existing DNA strand to complete the sequence.
A New Way to Control Stem Cell Fate Using Gene Circuits
Elina Kadriu | Feb 27, 2023 | 3 min read
Scientists engineered human pluripotent stem cells with synthetic gene circuits to control differentiation without human input.
Brown coral in shallow water branching upward with blue fish in front. 
Corals Upend Longstanding Idea About Genetic Inheritance
Natalia Mesa, PhD | Sep 1, 2022 | 4 min read
Most animals can’t pass on mutations that arise spontaneously throughout their lives—but Elkhorn corals can.
Key Strategies for Better Stem Cell Workflows
Solutions for Optimizing Stem Cell Therapy Development
Sartorius | 1 min read
Discover how process knowledge is integral to stem cell workflow improvement and optimization.
microscope image series showing synthetic embryo development
Mouse Embryo: No Sperm, Egg, or Uterus Required
Christie Wilcox, PhD | Aug 2, 2022 | 3 min read
Using stem cells and a bioreactor, researchers generated living embryos that survived for more than a week and began to develop internal organs.
Muscle immobilization leads to atrophy
Antioxidants Put the Pep Back in One’s Step
Niki Spahich, PhD | Jun 13, 2022 | 3 min read
Delivering antioxidants via extracellular vesicles to atrophied muscles restores them during rehabilitation.
Discover how counterflow centrifugation streamlines cell therapy workflows
Closed Cell Processing Systems for Cell Therapy Workflows
Thermo Fisher Scientific | 1 min read
Closed systems increase cell therapy manufacturing process efficiency.
Trichaptum abietinum growing on a pine log
Caught on Camera
The Scientist Staff | Jun 13, 2022 | 4 min read
See some of the coolest images recently featured by The Scientist
Female reproductive System Anatomy stock photo
Cells in the Ovary are Responsive Shape-Shifters
Roni Dengler, PhD | Apr 8, 2022 | 3 min read
Rounds of trial-and-error exploring the layer of cells covering the ovary leave open questions about stem cells that are associated with ovarian cancer.
 Learn how excessive oxygen availability during cell culture causes abnormal cell behavior 
What Oxygen Level Is Biologically Relevant For Cell Culture?
Thermo Fisher Scientific | 1 min read
Normoxic atmospheric conditions provide excessive oxygen availability, leading to abnormal cell behavior.
Stem Cells in Human Teeth Follow the Rules of Their Environment
Roni Dengler, PhD | Feb 7, 2022 | 2 min read
How stem cells in human teeth respond to different environmental conditions offers clues for regenerative medicine.
Stem Cell Transplant Treats Parkinson’s Disease in Monkeys
Roni Dengler, PhD | Feb 7, 2022 | 4 min read
Personalized stem cells improved motor symptoms and depression signs in monkeys modeling Parkinson’s disease, paving the way for trials in human patients.
Science Philosophy in a Flash - Paul George 
Science Philosophy in a Flash - Wired to Regenerate
Iris Kulbatski, PhD | 1 min read
Paul George shares how a dual career as a physician and scientist enriches his research.
istock
How to Grow a Mouse Embryo in a Dish
Roni Dengler, PhD | Aug 3, 2021 | 3 min read
Researchers are taking the concept of three-dimensional cell culture beyond single organoids to develop embryos from cells.
An underwater photo of the solitary tunicate Polycarpa mytiligera growing on a coral in the Red Sea
When Severed, This Solitary Tunicate Regrows as Three New Animals
Amanda Heidt | May 13, 2021 | 4 min read
While regeneration has long been the domain of colonial tunicates, a solitary species of sea squirt was able to regenerate into multiple, fully functional individuals within a month of being cut up.
Learn about innovations in tissue regeneration 
Stem Cell Engineering for Tissue Regeneration
The Scientist’s Creative Services Team | 1 min read
Innovative strategies drive stem cell repair of organ damage.
Human-Monkey Chimeras Shed Light on Development
Abby Olena, PhD | Apr 15, 2021 | 3 min read
Human stem cells injected into early monkey embryos proliferate and contribute to multiple cell lineages over 20 days of embryonic development.
Questions Raised About Widely Used Blood-Brain Barrier Model
Catherine Offord | Feb 16, 2021 | 6 min read
A study has sparked controversy by suggesting that cells made using a popular lab protocol have been misidentified, with potentially serious repercussions for brain research. Critics say the significance of the findings has been overstated.
A Brief History of Stem Cells
Scientific Breakthroughs with Stem Cells
Nele Haelterman, PhD | 1 min read
Discover the various ways scientists bolster stem cells to understand and cure disease.
a mockup of an at-home COVID-19 test in development
Top Technical Advances of 2020
Shawna Williams | Dec 18, 2020 | 3 min read
The pandemic spurred innovation in a variety of ways, from CRISPR-based diagnostics to cell biology benchwork at home.
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