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Illustration of newly discovered mechanism allowing kinesin to “walk” down a microtubule. A green kinesin molecule with an attached yellow fluorophore is shown passing through a blue laser as it rotates step by step along a red and purple microtubule, fueled by blue ATP molecules that are hydrolyzed into orange ADP and phosphate groups.
High-Resolution Microscope Watches Proteins Strut Their Stuff
Modification on a high-resolution fluorescent microscopy technique allow researchers to track the precise movements of motor proteins. 
High-Resolution Microscope Watches Proteins Strut Their Stuff
High-Resolution Microscope Watches Proteins Strut Their Stuff

Modification on a high-resolution fluorescent microscopy technique allow researchers to track the precise movements of motor proteins. 

Modification on a high-resolution fluorescent microscopy technique allow researchers to track the precise movements of motor proteins. 

microscopy

A normal human liver organoid (left) stained with blue and red next to a fatty liver organoid (right) with lipid droplets stained yellow.
Working Together to Battle Fatty Liver Disorders
Niki Spahich, PhD | Mar 24, 2023 | 6 min read
Benedetta Artegiani and Delilah Hendriks are forming a joint laboratory group to understand disease mechanisms and treatments through organoid models.
Discover a new way to analyze tissue samples
Diving Deeper into Tissue Samples with Spatial Context
Canopy Biosciences | Mar 15, 2023 | 1 min read
Scientists developed a standardized multiplex immunohistochemistry and RNA in situ hybridization protocol using ChipCytometryTM.
Visualizing apoptosis in a DU-145 cancer cell
Observing Cells in Their Natural State with Digital Holographic Cytometry
The Scientist’s Creative Services Team and Phase Holographic Imaging | 3 min read
Technological and engineering advances let researchers delve deeper into cell function and behavior in physiological and pathological settings.
A photo of a dish in which cells, which look like small dots, have been enlarged and stained to make them visible to the naked eye.
New Swelling Technique Makes Cells Visible to the Naked Eye
Kamal Nahas, PhD | Jan 19, 2023 | 4 min read
A new technique, called Unclearing Microscopy, physically inflates and then stains cells to circumvent the need for expensive microscopes.
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist Staff | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
Finding CAR T Cells in Solid Tumors by Single-Cell Resolution
Finding CAR T Cells in Solid Tumors at Single-Cell Resolution
The Scientist Creative Services Team in collaboration with Miltenyi Biotec | 1 min read
Rita Pfeifer will discuss visualizing and quantifying CAR T-cell infiltration into solid tumors with 3-D light sheet fluorescence microscopy (LSFM).
This is DishBrain, an in vitro system that combines human brain cells with artificial intelligence technology, which researchers at Australian biotech Cortical Labs recently trained to play the classic 1972 Atari video game Pong. Fluorescent markers show axons in green, neuron bodies in purple, dendrites in red, and all other cells in blue. Where multiple markers are present, colors are merged and typically appear as yellow or pink. Posted: October 12, 2022
Caught on Camera
The Scientist Staff | Dec 12, 2022 | 4 min read
See some of the coolest images recently featured by The Scientist.
slime mold spores
Science Snapshot: Breaking the Mold
Lisa Winter | Nov 3, 2022 | 1 min read
This image took 5th place at the 2022 Nikon Small World Photomicrography Competition.
Discover how to scale up cellular assays during drug discovery
High-Throughput Solutions for Lead Candidate Discovery
The Scientist’s Creative Services Team and Thermo Fisher Scientific | 1 min read
New technologies allow researchers to scale up assays for cellular functions.
Close up of spider
Science Snapshot: Legs for Days
Lisa Winter | Nov 2, 2022 | 1 min read
This image took 4th place at the 2022 Nikon Small World Photomicrography Competition.
Breast tissue shown in pink and yellow
Science Snapshot: Milking It
Lisa Winter | Oct 31, 2022 | 1 min read
This image took 2nd place at the 2022 Nikon Small World Photomicrography Competition.
Mapping the Brain in 3-D
Mapping the Brain in 3-D
Nathan Ni, PhD | 1 min read
3-D brain atlases help scientists better understand brain function in physiological and pathological situations.
Embryonic gecko hand
Science Snapshot: Show of Hands
Lisa Winter | Oct 28, 2022 | 1 min read
This image took the top prize at the 2022 Nikon Small World Photomicrography Competition.
3D imaging of organoid
Infographic: Generating Hundreds of 3D Organoid Images per Hour
Natalia Mesa, PhD | Oct 17, 2022 | 1 min read
By modifying a technique used to image single cells, researchers have managed to generate a super-resolution 3D image of a complete organoid in just seven seconds.
800x560-oct-5-2021
Technique Talk: Live-Cell Imaging Strategies to Quantify Phagocytosis
The Scientist Creative Services Team in collaboration with Sartorius | 1 min read
Discover how to image and quantitate phagocytosis in real time
Cellular therapy. 3d illustration
Expert JeWell-ry Designers
Natalia Mesa, PhD | Oct 17, 2022 | 3 min read
Analyzing organoids has proven slow and cumbersome for scientists. But a new technique may speed things up, producing 3D images of hundreds of organoids per hour.
pollen tubes releasing sperm into ovule
Science Snapshot: Go Forth and Multiply
Lisa Winter | Oct 6, 2022 | 1 min read
An honorable mention in the 2022 Nikon Small World in Motion competition shows thale cress sperm being released into the ovule.
Scientific Breakthroughs with Cryogenic Electron Microscopy
The Scientist’s Creative Services Team and Thermo Fisher Scientific | 1 min read
Structures made via cryo-EM give researchers insights into SARS-CoV-2, HIV, neurological disorders, cancer, and more.
Grayscale microscopic image of dying melanoma cells
Science Snapshot: Living Bubble Wrap
Lisa Winter | Oct 5, 2022 | 1 min read
This year’s fourth-place winner of the 2022 Nikon Small World in Motion competition shows dying melanoma cells.
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