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Artists' renditions of cancer cells and tRNA molecules superimposed over one another.
Long noncoding RNAs and Microproteins Can Spark Cancer—or Sometimes Squelch It
Noncoding RNAs and microproteins, once considered genomic noise, are turning out to be critical to the progression of some types of cancer.
Long noncoding RNAs and Microproteins Can Spark Cancer—or Sometimes Squelch It
Long noncoding RNAs and Microproteins Can Spark Cancer—or Sometimes Squelch It

Noncoding RNAs and microproteins, once considered genomic noise, are turning out to be critical to the progression of some types of cancer.

Noncoding RNAs and microproteins, once considered genomic noise, are turning out to be critical to the progression of some types of cancer.

microRNAs

Cells with miRNA activity reporter glowing
MicroRNAs Can Boost Gene Expression: Study
Holly Barker, PhD | Nov 15, 2022 | 3 min read
The tiny strings of RNA promote translation of a protein implicated in cancer, a hint they could regulate gene expression in more ways than previously thought.
Illustration from the epigenetics and the genome infographic
Infographic: How Epigenetic Marks Can Change the Genome
Katarina Zimmer | Nov 1, 2022 | 2 min read
Although epigenetic changes were long thought to largely act on the genome, rather than as part of it, research is now showing that these patterns can, directly or indirectly, change the genetic code.
Cellular DNA and epigenetics
Do Epigenetic Changes Influence Evolution?
Katarina Zimmer | Nov 1, 2022 | 10+ min read
Evidence is mounting that epigenetic marks on DNA can influence future generations in a variety of ways. But how such phenomena might affect large-scale evolutionary processes is hotly debated.
Conceptual image showing molecules making up a brain shape
The Noncoding Regulators of the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 10+ min read
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.
Illustration of RNAs
Infographic: Noncoding RNA in the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 4 min read
Neurologically important noncoding RNAs come in many shapes and sizes.
Arabidopsis thaliana flowers
Plants Use RNA to Talk to Neighbors
Alejandra Manjarrez, PhD | Oct 21, 2021 | 4 min read
A study finds that plants sharing the same growth medium can exchange microRNAs that silence genes in the recipient, suggesting the nucleic acids may act as signaling molecules.
Bisrat Debeb Models How Cancer Spreads to the Brain
Catherine Offord | Apr 1, 2021 | 3 min read
From his student days in veterinary medicine in Ethiopia to running a lab on metastasis at MD Anderson Cancer Center, Debeb has a passion for understanding how living things work.
rugby, concussion, brain injury, concussion, trauma, saliva, spit, test, noninvasive, diagnostic, microRNA, small noncoding RNA, PCR, RNA
Simple Spit Test Could Diagnose Concussions
Asher Jones | Mar 24, 2021 | 2 min read
A noninvasive saliva test accurately identified concussions in a study of hundreds of rugby players.
a woman sitting on a bed with her head in her arms
Blood MicroRNA Patterns Linked to Chronic Fatigue Syndrome
Katarina Zimmer | Nov 30, 2020 | 5 min read
A finding of distinct patterns of gene-regulating RNA snippets in the blood of ME/CFS patients in response to a stress test could pave the way for a diagnostic tool for the condition and help untangle its underlying mechanisms.
Q&A: How Animals Change in Space
Jef Akst | Nov 25, 2020 | 4 min read
Weill Cornell Medicine geneticist Christopher Mason speaks with The Scientist about a bolus of new work on the physiological, cellular, and molecular effects of leaving Earth.
the knees of a woman sitting on grass outside
Adult Humans Can Regenerate Cartilage: Study
Shawna Williams | Oct 10, 2019 | 2 min read
Collagen inside ankles has more turnover than that in hips, thanks to the action of microRNAs.
Speaking of Cancer Research
Tanya Lewis, Jef Akst, and Mary Beth Aberlin | Apr 20, 2016 | 2 min read
A selection of notable quotes from the annual American Association for Cancer Research meeting
Sperm RNAs Transmit Stress
Kate Yandell | Oct 19, 2015 | 3 min read
Stressed male mice can pass on an abnormal stress response to their offspring via microRNAs found in sperm, a study shows.
Benjamin tenOever: Going Viral
Kerry Grens | Jan 1, 2014 | 3 min read
Professor, Microbiology, Icahn School of Medicine at Mount Sinai. Age: 36
Circular RNA Surprise
Dan Cossins | Feb 28, 2013 | 2 min read
Previously enigmatic circular RNAs have been found to influence gene expression by binding to and blocking another class of regulatory RNA, the microRNAs.
Brain Evolution at a Distance
Hannah Waters | Dec 6, 2011 | 3 min read
Gene expression controlled from afar may have spurred the spurt in brain evolution that led to modern humans.
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