metabolites

The expansion of mucus-degraders in the mouse gut—possibly due to poor nutrition—thins the colon’s mucus layer and may weaken defenses against blood-infecting microbes.

A sugar that’s less abundant in the blood of people with diabetes binds to SARS-CoV-2’s spike protein and disrupts the virus’s ability to fuse with cells.  

The unique odor profiles of tumors can be used to develop diagnostic sensing tools.

Microbes designed to produce specific immunomodulatory metabolites could give immunotherapy a boost.

Intestinal bacteria contribute to the effect of stimulating environments on the brain’s ability to adapt, a study concludes.

The gastrointestinal tracts of people with major depressive disorder harbor a signature composition of viruses, bacteria, and their metabolic products, according to the most comprehensive genomic and metabolomic analysis in depression to date.

The study of diet, long plagued by inaccuracies in self reports, is entering a new age of precision with the methods of metabolomics.

Nutrition researchers are beginning to use metabolomics to determine how healthy subjects’ diets are, and even to reveal specific properties of the foods they eat.

Firefighters who didn’t develop obstructive airway disease after the World Trade Center attacks had higher levels of omega-3 fatty acids and other factors that hint at possible protective effects of diet.

A newfound family of metabolites emits green light in response to the blue light of the deep ocean, causing certain sharks to glow.

Researchers seek to untangle the biological mechanisms linking resident microbes to our hearts—and to harness them therapeutically.

Emerging technologies help researchers draw mechanistic links between metabolism and epigenetic modification of DNA.

Out of 25,000 features originally detected by metabolic profiling of E. coli, fewer than 1,000 represent unique metabolites, a study finds.

Obesity-associated microbiome composition can persist after weight loss, affecting the exchange of metabolites between a mouse and its resident bugs, researchers report.

A comprehensive analysis of human urine identifies more than 3,000 metabolites. 

Obesity drives an alteration of the gut microbiome, leading to the secretion of metabolites associated with the development of liver cancer.