melanoma

This year’s fourth-place winner of the 2022 Nikon Small World in Motion competition shows dying melanoma cells.

When coated with positively charged particles, the bacteria shuttled antigens out of tumors and activated the immune system, a study finds.

Targeted cancer therapy may jeopardize the effectiveness of subsequent immunotherapy by reducing dendritic cell numbers and activation, according to study of mice and patient samples.

After controlling for high levels of bacterial contamination in their lab and reagents, researchers detect microbial genetic material in plasma samples from healthy people and cancer patients.

The color morph’s bright yellow hue and its propensity for skin tumors both likely stem from a gene implicated in a dangerous form of human skin cancer, suggesting the animals could make an ideal model for studying the disease.

Researchers say evidence of hybridization between leukocytes and cancer indicates that this is a primary means of metastasis. Others disagree.

While machine learning could improve detection of tumors at their earliest stages, it also risks identifying malignancies that would never cause the patient any harm.

Over nearly 50 years, the Monell Chemical Senses Center chemist investigated a range of topics, from the smell of cancer to body odor’s effects on human physiology and behavior.

A deep neural network can help determine how likely cancer cells are to metastasize.

The field is young, but predicting antigens produced by patients’ malignant cells could yield successful treatments for individuals with a range of cancer types.

A deep learning program can identify cells with higher metastatic potential based on the way they look and move.

Merck’s Keytruda extended the lives of lung cancer patients by several months and appeared to stop the progression of advanced melanoma.  

Selected Images of the Day from the-scientist.com

A molecule produced by a strain of Staphylococcus epidermis interferes with DNA synthesis.

The treatment also curbed the growth of nearby metastases that did not receive the drug.

When certain melanocyte stem cells are exposed to UV rays, a molecular cascade can trigger melanoma, scientists find in mice.

In mice, the tumor cells are able to thwart the immune response that would kill them—but immunotherapy prevented the return of melanoma.

Glowing cells mark the routes of tumor spread by way of newly formed lymph vessels. 

A new approach to immunotherapy finds that the immune-cell clonotypes that come to the rescue start out at very low frequencies.