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Illustration of light blue speckled DNA helix on a dark background
Study Nearly Doubles Known Cancer-Linked Mutational Signatures
Analyzing the whole genome sequences of more than 18,000 tumors, researchers catalog nearly 60 new patterns of mutations that could inform cancer treatment.
Study Nearly Doubles Known Cancer-Linked Mutational Signatures
Study Nearly Doubles Known Cancer-Linked Mutational Signatures

Analyzing the whole genome sequences of more than 18,000 tumors, researchers catalog nearly 60 new patterns of mutations that could inform cancer treatment.

Analyzing the whole genome sequences of more than 18,000 tumors, researchers catalog nearly 60 new patterns of mutations that could inform cancer treatment.

genomics

A scientific illustration of a Christmas Island rat
Genome Spotlight: Christmas Island Rat (Rattus macleari)
Christie Wilcox, PhD | Mar 24, 2022 | 4 min read
The near-complete genome of a recently extinct rodent elucidates the potential—and difficulties—of resurrecting species.
Deborah Nickerson
Genome Pioneer Deborah Nickerson Dies at 67
Amanda Heidt | Feb 9, 2022 | 3 min read
The University of Washington researcher leveraged data from the Human Genome Project to identify genes underlying various health conditions and advance precision medicine.
Neoantigen Prediction for Precision Immunotherapies
Neoantigen Prediction for Precision Immunotherapies 
The Scientist’s Creative Services Team | 2 min read
Learn about the tools and resources researchers use to define, discover, and deploy anti-tumor immunotherapies.
A fresh, peeled lychee fruit held above a harvest of fresh lychees
Genome Spotlight: Lychee (Litchi chinensis)
Christie Wilcox, PhD | Jan 27, 2022 | 3 min read
Whole genome sequences reveal multiple domestications of this agriculturally important tree and may hold the secrets to producing the sweet fruit year round.
Microscopic view of salmonella
Caught on Camera
The Scientist Staff | Jan 20, 2022 | 1 min read
Selected Images of the Day from the-scientist.com
Learn How Multiomics Drives Biotherapeutic Discovery and Development
Advancing Biotherapeutics with Multiomics
The Scientist’s Creative Services Team and Tecan | 1 min read
Explore how biomolecular processes drive health and disease.
Organisms from infographic about transposable elements
Infographic: How Transposable Elements Can Shape Evolution
Christie Wilcox, PhD | Jan 17, 2022 | 2 min read
The movements of so-called jumping genes can generate the genetic diversity needed to drive evolutionary change in populations over time.  
A notecard with outdated names of prokaryotic phyla crossed out and replaced with the newer names.
Newly Renamed Prokaryote Phyla Cause Uproar
Dan Robitzski | Jan 4, 2022 | 10+ min read
The International Committee on Systematics of Prokaryotes recently pulled the rank of phylum into its code of official nomenclature. Experts say the move will help standardize science in the long run but potentially disrupt research now.
Sartorius
Understanding the Blood Cancer Genomic Landscape 
The Scientist’s Creative Services Team | 1 min read
Information about the genomic and immunological characteristics of blood cancers is helping scientists discover and develop new immunotherapies.
Collage of those featured in the article
Remembering Those We Lost in 2021
Lisa Winter | Dec 23, 2021 | 5 min read
As the year draws to a close, we look back on researchers we bid farewell to, and the contributions they made to their respective fields.
An illustration shows circular red blood cells running into a yellow cholesterol blockage in a transverse section of an artery on a blue and purple background
Genetic Variant Discovered in Amish Protects from Heart Disease
Abby Olena, PhD | Dec 2, 2021 | 3 min read
Researchers link a missense mutation in the B4GALT1 gene to lower levels of LDL cholesterol and the blood clotting factor fibrinogen.
Discover the microbiome’s role in diabetes 
A Question of Balance: How the Gut Microbiome Influences Diabetes
The Scientist’s Creative Services Team | 1 min read
The presence of beneficial or detrimental microbes pulls the host toward health or disease.
small, circular bones individually labeled and packaged in plastic bags
2,000-Year-Old Salmon DNA Reveals Secret to Sustainable Fisheries
Dan Robitzski | Nov 29, 2021 | 5 min read
Genomic analysis of ancient chum salmon bones and cultural knowledge from the Tsleil-Waututh Nation suggest that people in the Pacific Northwest managed fisheries for thousands of years by harvesting males and releasing females.
orange and blue cell image
Woman’s Body Appears to Rid Itself of HIV
Chloe Tenn | Nov 18, 2021 | 3 min read
Researchers report what appears to be the second case of a person’s immune system clearing the virus on its own.
Technique Talk: Single-Cell Spatial Transcriptomics with Cleavable Fluorescent Probes 
Single-Cell Spatial Transcriptomics with Cleavable Fluorescent Probes 
The Scientist’s Creative Services Team | 1 min read
In this webinar, Jia Guo discusses the basics of in situ hybridization and how to use novel fluorescent probes for ultra-sensitive single-cell resolution in situ genomics.
Conceptual image of gene expression in DNA
Enhancers: Conserved in Activity, Not in Sequence
Jack J. Lee | Nov 1, 2021 | 8 min read
Certain stretches of DNA that regulate gene expression have evolved differently from protein-coding genes.
man standing in front of gene sequencing machines
Q&A: Nearly Every Single Human Gene Can Be Linked to Cancer
Dan Robitzski | Oct 29, 2021 | 6 min read
The Scientist spoke with University of Liverpool aging and longevity researcher João Pedro de Magalhães about how human biases can influence scientific priorities and outcomes in genetics.
Methylation Sequencing to Identify Potential Cancer Biomarkeres 
Methylation Sequencing in Cancer Detection
The Scientist’s Creative Services Team and Twist Bioscience | 1 min read
Discover how efforts to uncover the genome's methylation patterns advance cancer detection.
Common vampire bats on a black background
The Genes Vampires Lost
Alejandra Manjarrez, PhD | Oct 28, 2021 | 5 min read
According to a preprint, the common vampire bat lacks 13 genes present in other bat species, which may help explain their blood-only diet and other curious aspects of their lifestyle.
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