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Image shows photorhabdus virulence cassettes (green) binding to insect cells (blue) prior to injection of payload proteins. 
Engineered Bacterial “Syringes” Can Deliver Drugs Into Human Cells
Researchers repurpose tiny bacterial injection systems to specifically inject a wide variety of proteins into human cells and living mice.
Engineered Bacterial “Syringes” Can Deliver Drugs Into Human Cells
Engineered Bacterial “Syringes” Can Deliver Drugs Into Human Cells

Researchers repurpose tiny bacterial injection systems to specifically inject a wide variety of proteins into human cells and living mice.

Researchers repurpose tiny bacterial injection systems to specifically inject a wide variety of proteins into human cells and living mice.

drug delivery systems

Red blood vessels that decrease in diameter as they radiate outward are pictured on a pink and white surface
Antisense Oligonucleotides Cross Rodents’ Blood-Brain Barrier
Abby Olena, PhD | Aug 18, 2021 | 3 min read
RNA-DNA complexes that were modified with cholesterol made it into the brains of rats and mice, where they knocked down target genes.
Infographic: Building Bacteria to Fight Cancer
Simone Schuerle and Tal Danino | Apr 1, 2020 | 3 min read
Researchers are engineering microbes to deliver therapeutics specifically to tumors, maximizing the treatments’ efficacy while minimizing side effects.
Bacteria as Living Microrobots to Fight Cancer
Simone Schuerle and Tal Danino | Apr 1, 2020 | 10+ min read
Autonomous, living microrobots that seek and destroy cancer are not as futuristic as one might imagine, thanks to a fusion of robotics and synthetic biology.
Laser-Triggered Nanobubbles Blast a Path into Biofilms
Jonathan Wosen | Apr 1, 2020 | 4 min read
Researchers could one day use the method to deliver antibiotics to topical wounds infected by hard-to-treat masses of bacteria.
smartphone controlled device implanted in mouse brain
Image of the Day: Smartphone-Controlled Brains
Nicoletta Lanese | Aug 7, 2019 | 1 min read
A device implanted into mice can modulate brain circuit activity over long periods of time.
Microneedle patch delivers liquid medications
Image of the Day: Artificial Snake Bite
Nicoletta Lanese | Aug 6, 2019 | 1 min read
A microneedle delivers liquid medicines through tiny, fang-like points.
DNA-Delivered Antibodies Fight Off Lethal Bacterial Infection
Catherine Offord | Oct 3, 2017 | 4 min read
Mice receiving the treatment produced their own monoclonal antibodies and survived infection with the life-threatening pathogen Pseudomonas aeruginosa.
Tiny Motors Deliver Ulcer Medication in Mouse Stomachs
Shawna Williams | Aug 16, 2017 | 1 min read
The mini machines treated infection somewhat better than antibiotics plus the typical proton pump inhibitor medication. 
Image of the Day: Teeny Tiny Delivery Balls
The Scientist Staff | Aug 3, 2017 | 1 min read
Scientists designed autonomous nanovesicles capable of following glucose concentration gradients, even through the blood brain barrier in rats.
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