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Illustration of woman looking at floating cells through a telescope
Opinion: New Diabetes Drug Signals Shift to Preventing Autoimmunity
A therapy for type 1 diabetes is the first to treat patients before symptoms appear, paving the way toward preventing this and other autoimmune diseases.
Opinion: New Diabetes Drug Signals Shift to Preventing Autoimmunity
Opinion: New Diabetes Drug Signals Shift to Preventing Autoimmunity

A therapy for type 1 diabetes is the first to treat patients before symptoms appear, paving the way toward preventing this and other autoimmune diseases.

A therapy for type 1 diabetes is the first to treat patients before symptoms appear, paving the way toward preventing this and other autoimmune diseases.

diabetes

A doctor checking a patient’s blood sugar levels using a glucometer on their ring finger.
An Implantable Device for Type 1 Diabetes Treatment
Elina Kadriu | Apr 18, 2023 | 3 min read
Engineering of a novel device to treat T1D, featuring local immunosuppression and a vascularized cell reservoir to prolong islet cell survival.
a trio of infant mice, two brown mice on the ends and one white mouse in the middle
Mice Pass Epigenetic Tweaks to Pups
Katherine Irving | Feb 17, 2023 | 5 min read
An engineered methylation pattern persisted for four generations of mice, demonstrating transgenerational epigenetic inheritance can occur in mammals.
Discover the microbiome’s role in diabetes 
A Question of Balance: How the Gut Microbiome Influences Diabetes
The Scientist’s Creative Services Team | 1 min read
The presence of beneficial or detrimental microbes pulls the host toward health or disease.
A Nile rat sitting atop fruits
Genome Spotlight: Nile Rat (Avicanthis niloticus)
Christie Wilcox, PhD | Nov 23, 2022 | 4 min read
A reference sequence for this emerging model organism will facilitate research on type 2 diabetes and the health effects of circadian rhythm disruption.
Illustration of pink and blue DNA molecules.
Historic Adaptations May Now Make Us Susceptible to Disease
Dan Robitzski | Sep 16, 2022 | 5 min read
Researchers made the find using an algorithm that purportedly distinguishes between mutations that were selected for and those that came along for the ride by coincidence, a feat that has long eluded scientists.
VAI
Exposed: Environmental Echoes in Health - A Special Podcast Series
The Scientist’s Creative Services Team and Van Andel Institute | 2 min read
Epigenetic experts discuss how environment and diet leave lasting impressions on the human genome.
Bright purple and orange lactobacillus bacteria.
How a Specific Gut Bacterium May Cause Type 1 Diabetes
Dan Robitzski | Aug 25, 2022 | 5 min read
A bacterium that produces an insulin-like peptide can give mice type 1 diabetes, and infection with the microbe seems to predict the onset of the disease in humans, a study finds.
Micrograph of a beta cell, where insulin granules are shown as blue small balls, mitochondria are colored green, and a fraction of the cell nucleus appears in purple.
Diabetes Linked to Malnutrition Is Metabolically Unique: Study
Alejandra Manjarrez, PhD | Jun 16, 2022 | 5 min read
Results from a small sample of Indian males suggest that lean individuals with a history of malnutrition suffer from a distinct type of diabetes characterized by a defect in insulin secretion.
Peripheral blood mononuclear cells surrounded by red blood cells in circulating blood.
Accelerating Immune Research with Cryopreserved Peripheral Blood Mononuclear Cells
The Scientist’s Creative Services Team and MilliporeSigma | 3 min read
Commerically-available peripheral blood mononuclear cells offer a well-characterized, accessible, and consistent model for immunology and therapeutic development.
Group of cells stained in either blue or green in a black background.
Diabetes Marker Linked to COVID-19 Severity in Mice
Alejandra Manjarrez, PhD | May 16, 2022 | 3 min read
A sugar that’s less abundant in the blood of people with diabetes binds to SARS-CoV-2’s spike protein and disrupts the virus’s ability to fuse with cells.  
hands of a person checking their blood glucose level with a monitor
Growing Evidence Ties COVID-19 to Diabetes Risk
Bianca Nogrady | May 3, 2022 | 7 min read
Studies suggest SARS-CoV-2 infection could trigger the development of diabetes in some people, even those with no other risk factors.
Staphylococcus aureus bacteria on the skin
The Scientist Speaks - Virulence Meets Metabolism: The Unique Evolution of Staphylococcus aureus
Niki Spahich, PhD | 1 min read
Anthony Richardson discusses what makes Staph especially dangerous for people with diabetes.
A Northern Bahamian Rock Iguana cranes its neck to eat a grape that’s speared on the end of a stick.
Grape-Doling Tourists Gave Endangered Iguanas High Blood Sugar
Dan Robitzski | Apr 21, 2022 | 3 min read
Research finds that a high-sugar diet supplied by tourists is giving Bahamian rock iguanas the lizard equivalent of high blood sugar.
Arthur Riggs smiles for the camera
Geneticist Arthur Riggs Dies at 82
Lisa Winter | Apr 14, 2022 | 2 min read
His research paved the way for the development of synthetic insulin to treat diabetes.
Cell Culture Advances Fuel Disease Research
The Scientist’s Creative Services Team | 1 min read
New twists to an old technique reveal a better understanding of disease pathology and new therapeutic avenues.
Four white, circular pills balance on their side in front of a pink background.
Metformin Prescriptions Linked to Sons’ Birth Defects
Dan Robitzski | Mar 29, 2022 | 2 min read
A new cohort study finds that boys whose fathers took the type 2 diabetes drug metformin three months before their conception were more likely to have a birth defect.
M. Mueckler looking at the camera in front of his microscope in 1998.
Cellular Biologist Michael Mueckler Dies at 67
Lisa Winter | Aug 18, 2021 | 1 min read
His work centered on the mechanisms of glucose transport into cells.
High Content Phenotypic Screening and Analysis Enhances Drug Discovery
The Scientist’s Creative Services Team | 1 min read
Molly Shoichet and Bridget Wagner discuss strategies for using phenotypic screening to identify novel agents against diseases such as cancer and diabetes.
Fat Tissue Reorganizes During Pregnancy
Catherine Offord | Aug 1, 2021 | 3 min read
Researchers identify a protein that promotes changes in adipose tissue in vitro and in pregnant mice and may help protect against gestational diabetes in humans.
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