CRISPR

A new CRISPR screening technology allows scientists to recreate tumor heterogeneity in vivo and study how it affects all aspects of cancer biology.

A new method has allowed researchers to conduct the first gene knock-out and knock-in edits on cockroaches and may extend to many other insects.

A brain area of Aedes aegypti responds specifically to components of human sebum, a study finds.

A collaboration between friends led to a cautionary finding about CRISPR’s effect on cells.

CRISPR-mediated removal of HIV can create small, infectious DNA molecules.

A first-of-its-kind gene therapy dramatically reduced misfolded protein levels in some clinical trial participants for up to six months and reduced levels in all participants for up to a year.

The US Patent and Trademark Office has once again decided that the institute has priority over the University of California and collaborators regarding intellectual property rights for CRISPR-Cas9 gene editing in eukaryotes. But the fight over the technique isn’t over.

RNA editing has been in DNA editing’s shadow for nearly a decade, but recent investments in the technology could bring it into the limelight.

CRISPR-Cas9’s molecular scissors—thus far limited to the lab bench—may soon find themselves at work directly in the human body.

Taking inspiration from her PhD research, Ana Moreno formed a company where scientists use CRISPR to treat chronic pain

Ancient and modern genomes reveal that a variant of the human growth hormone receptor likely helped our ancestors survive when food was scarce.

The results reveal evolutionary relatives of the Cas9 enzyme now used extensively in biotechnology.

The makers of the CRISPR-based testing platform, called miSHERLOCK, say it could enable people at home or physicians in resource-limited environments to detect SARS-CoV-2—and eventually, other pathogens.