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Microscopy image of blue stained cohesin proteins.
Mutated Cohesin Throws DNA Splicing out of Whack, Resulting in Cancer
Cohesin mutations cause dysregulations in alternative splicing, contributing to tumor initiation and progression, a study finds. 
Mutated Cohesin Throws DNA Splicing out of Whack, Resulting in Cancer
Mutated Cohesin Throws DNA Splicing out of Whack, Resulting in Cancer

Cohesin mutations cause dysregulations in alternative splicing, contributing to tumor initiation and progression, a study finds. 

Cohesin mutations cause dysregulations in alternative splicing, contributing to tumor initiation and progression, a study finds. 

colorectal cancer

Pink- and purple-stained cells clustered into glands
Phenotypic Variation in Cancer Cells Often Not Due to Mutations
Jef Akst | Oct 26, 2022 | 3 min read
Most differences in gene expression among cells within a tumor are likely due to environment or noise, a study suggests. 
Fluorescent microscopy of a healthy intestinal organoid and a tumor spheroid
Internal Clock Disruptions Increase Colon Cancer Risk in Mice
Shafaq Zia | Aug 19, 2022 | 3 min read
Disturbing circadian rhythms in organoids and mice increases intestinal tumor growth, findings that may explain a recent rise in colon cancer among young adults, the researchers behind the work say.
Caught on Camera
The Scientist Staff | Dec 1, 2019 | 1 min read
Selected Images of the Day from the-scientist.com
Cancer Cells Increase DNA Mutations to Evade Treatment
Abby Olena, PhD | Nov 7, 2019 | 3 min read
Colorectal tumor cells limit their DNA repair in response to a targeted therapy, giving them a greater chance to develop resistance to the drug.
Image of the Day: Patient-Derived Organoids
Emily Makowski | Oct 10, 2019 | 1 min read
Three-dimensional tissue cultures grown from cancer patients’ own tumors can predict responses to the drug irinotecan.
polyp colorectal cancer
There’s a Troubling Rise in Colorectal Cancer Among Young Adults
Katarina Zimmer | Aug 26, 2019 | 7 min read
Some experts blame our modern, sugary diet, while others think that gut microbiome changes and sedentary lifestyles may play a role. Altogether, the causes are far from clear.
Henry Lynch obituary cancer genetics hereditary syndrome breast ovarian
Henry Lynch, Leader in Cancer Genetics, Dies
Chia-Yi Hou | Jun 7, 2019 | 2 min read
The Creighton University researcher discovered the genetic basis of hereditary breast-ovarian cancer syndrome.
Genetically Personalized Fruit Flies Screen for Cancer Drugs
Ruth Williams | May 22, 2019 | 4 min read
Fly avatars bearing multiple genetic changes akin to those of a cancer patient lead to a tailor-made treatment that has shrunk the patient’s tumors.
Mouse organoid Actin phalloidin tumor suppressors colorectal cancer
Image of the Day: Colorful Colonoids
Chia-Yi Hou | Apr 18, 2019 | 1 min read
Organoids grown from a mouse’s colon will be used to screen drugs for colorectal cancer.
Voodoo Dolls, Roller-Coasters for Kidney Stones Win at Ig Nobels
Ashley Yeager | Sep 14, 2018 | 2 min read
The awards for comical but practical scientific discovery also include cannibalism and self-colonoscopy.
New Liquid Biopsy Detects Cancer at Earlier Stages Than Currently Possible
Jim Daley | Jun 1, 2018 | 2 min read
The test can pick up several types of cancer, including pancreatic and ovarian, years before symptoms appear.
Latest Reproducibility Project Study Fails to Replicate
Kerry Grens | Mar 13, 2018 | 2 min read
Researchers did not observe the same link between a bacterium and human colon cancer that prior investigators had reported.
Liquid Biopsy Test May Help Screen Eight Types of Cancer
Jim Daley | Jan 21, 2018 | 2 min read
The new diagnostic works by identifying cancer-associated proteins and DNA in patient blood.
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