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Bladder epithelial tissue, where cell junctions are shown in green and nuclei in blue. This was grown in vitro from cells taken from mice with chronic cystitis.
Bladder ‘Memory’ Influences Urinary Tract Infection Recurrence in Mice
Urinary tract infections leave permanent epigenetic marks in the mouse bladder epithelium, reprogramming its response to subsequent infections, a study finds.
Bladder ‘Memory’ Influences Urinary Tract Infection Recurrence in Mice
Bladder ‘Memory’ Influences Urinary Tract Infection Recurrence in Mice

Urinary tract infections leave permanent epigenetic marks in the mouse bladder epithelium, reprogramming its response to subsequent infections, a study finds.

Urinary tract infections leave permanent epigenetic marks in the mouse bladder epithelium, reprogramming its response to subsequent infections, a study finds.

cell death

fuorescence microscopy of kidney tissue
Artificial Blood Breathes New Life Into Dead Pigs’ Cells
Andy Carstens | Aug 3, 2022 | 2 min read
A study’s authors say their oxygenating cocktail may lead to technologies that preserve organs in deceased people for longer periods for transplantation.
A drawing of pseudostratified gut epithelial cells in the early intestines, cells in red and nucleus in purple.
Move Over Apoptosis: Another Form of Cell Death May Occur in the Gut
Natalia Mesa, PhD | May 18, 2022 | 6 min read
Though scientists don’t yet know much about it, a newly described process called erebosis might have profound implications for how the gut maintains itself.
Programmed Cell Death: Mechanisms for Cellular Self-Destruction
Programmed Cell Death: Mechanisms for Cellular Self-Destruction
Elina Kadriu | 6 min read
Cells use a variety of programmed cell death (PCD) mechanisms to maintain homeostasis, including apoptosis, necroptosis, and pyroptosis.  
Diffuse star-like shapes with regions in purple, green, and both colors overlapped.
Tumor Cells on Brink of Death May Trigger Metastasis
Alejandra Manjarrez, PhD | Mar 25, 2022 | 5 min read
A new study reports that human colon cancer cells at imminent risk of death can instead develop characteristics needed to colonize new parts of the body.
dave david schubert salk institute neurobiology cell lines alzheimer's disease curcumin j147 fisetin
Neurobiologist Dave Schubert Dies
Kerry Grens | Aug 24, 2020 | 2 min read
The Salk professor developed the institute’s first neurobiology lab and used it to develop cell lines, describe amyloid β toxicity, and screen for compounds that protect against neurodegeneration.
Why might cells die or fail to thrive in culture?
Why Might Cells Die or Fail to Thrive in Culture?
MilliporeSigma | 1 min read
Learn more about cell culture best practices.
an explosion of red light radiating out from a core
Could Curbing Runaway Immune Responses Treat COVID-19?
Shawna Williams | Apr 21, 2020 | 5 min read
Drugs targeting patients’ immune systems, rather than the virus itself, could be key to recovery from severe cases of the disease, some researchers suggest.
necroptosis apoptosis cancer t cell immunotherapy
Dying Cells Push the Mouse Immune System into Killing Tumors
Katarina Zimmer | Jun 21, 2019 | 4 min read
Introducing either necroptotic cells or an enzyme that triggers necroptosis can wipe out cancer.
telomere length sticky stuck chromosome aging apoptosis cancer cell oxidative stress
Image of the Day: Sticky Telomeres
Chia-Yi Hou | May 16, 2019 | 1 min read
Telomeres in cancer cells exposed to oxidative stress got shorter and stickier.
The World Within
Bob Grant | Feb 1, 2019 | 3 min read
Internalizing the environment might be the next step in humans’ relationship with our planet.
cell death infographic
Infographic: How Cells Cheat Death
Charles Q. Choi | Feb 1, 2019 | 3 min read
Apoptosis and other types of programmed cell death appear to be reversible.
Cell Death Processes Are Reversible
Charles Q. Choi | Feb 1, 2019 | 10+ min read
Molecular programs can rescue cells already engaged in the process of apoptosis or other forms of programmed cell death.
Image of the Day: Pseudomonas Autophagy
The Scientist Staff and The Scientist Staff | Mar 30, 2018 | 1 min read
Researchers identify antibacterial functions of cell death in Arabidopsis when the plant is infected with Pseudomonas.  
John Sulston, Human Genome Project Leader, Dies
Kerry Grens | Mar 11, 2018 | 2 min read
The biologist earned a Nobel Prize in 2002 for his work on C. elegans.
Image of the Day: Dial M for Murder
The Scientist Staff | Aug 16, 2017 | 1 min read
M proteins from Streptococcus bacteria selectively kill mouse macrophages and human macrophage-like cells by prompting cell death.
Dying Light Marks the Spot
Catherine Offord | Mar 28, 2016 | 2 min read
Drug-delivering nanoparticles designed to glow when their target cells die can report on the effectiveness of cancer therapies within just a few hours of treatment, a mouse study shows.
Immune Cells Can Deliver Deadly Packages
Amanda B. Keener | Sep 8, 2015 | 3 min read
Much of the CD4+ T-cell death that occurs during HIV infection may be caused by direct delivery of the virus from neighboring cells, a study shows.
Inner Ear Undertakers
Kerry Grens | Sep 1, 2015 | 2 min read
Support cells in the inner ear respond differently to two drugs that kill hair cells.
Autophagy Revives Dying Cancer Cells
Kerry Grens | Apr 7, 2014 | 1 min read
Self digestion thwarts self destruction.  
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