By packaging lipid nanoparticles with elements that decrease the fibrous nature of solid tumors, researchers can deliver CRISPR therapies in a more efficient manner.
From histopathology to multiplex immunohistochemistry and spatial transcriptomics, learn how to obtain the appropriate profiling depth to match cancer classification needs.
Researchers found that naturally-occurring CD7-negative T cells avoid self-destruction and are good effectors in CAR T therapy for T cell blood cancers.
Researchers determined the safety and antitumor ability of genetically engineered CAR T cells that circumvent immune suppression in a prostate cancer phase I clinical trial.
An in situ map of copy number variations in prostate tissue reveals that purportedly cancerous genomic changes frequently occur in the healthy tissue surrounding tumors.
Disturbing circadian rhythms in organoids and mice increases intestinal tumor growth, findings that may explain a recent rise in colon cancer among young adults, the researchers behind the work say.
At Brigham and Women’s Hospital, the cancer biologist is combining research into the tumor microenvironment with the principles of neuroscience to tease apart how cancers grow—and how to stop them.
![jigsaw puzzle with magnifying glass over the word "metastasis" ](https://cdn.the-scientist.com/assets/articleNo/70540/aImg/47882/49929-800x5607-t.jpg "jigsaw puzzle with magnifying glass over the word "metastasis" ")
