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breast cancer

Hormone Therapy Triggers Male Gene Patterns in Transgender Men’s Cells

Holly Barker, PhD | Mar 15, 2023 | 3 min read

A study deepens the scientific understanding of how androgens influence breast tissue, which may offer clues to treating breast cancer.

A colored microscopy image of a dividing breast cancer cell

Transfer RNAs Have a Surprising Role in Breast Cancer Growth

Natalia Mesa, PhD | Jan 5, 2023 | 4 min read

A particular leucine-ferrying tRNA is more abundant in cancerous cells than healthy ones, and lowering its levels inhibits cancer growth, a study finds.

A colorful bouquet of fruits and vegetables in a mesh canvas bag.

Beyond Individual Nutrients: Complex Diet and Cancer Connections

Deanna MacNeil, PhD | 4 min read

Scientists develop cancer nutrition guidelines based on research examining how dietary patterns affect cancer risk and prevention.

A purple-stained section of an invasive breast cancer growth. The dark purple non-fatty tissue takes up the majority of the frame, and pale purple circular tumors grow in ducts in the bottom left.

Harboring Hard and Soft Cells Lets Tumors Grow and Metastasize Simultaneously

Katherine Irving | Oct 17, 2022 | 4 min read

Islands of rigid cells within a matrix of soft ones allow tumors to be both solid and fluid, granting them toughness without losing the ability to break apart.

jigsaw puzzle with magnifying glass over the word "metastasis"

Breast Cancer Cells Retrain T Cells to Invade Specific Tissues

Nele Haelterman, PhD | Sep 26, 2022 | 3 min read

Scientists discover tumor-associated T cells that drive breast cancer metastasis to lymph nodes.

Setting Better Traps for PARP Inhibitors

The Scientist’s Creative Services Team and BPS Bioscience | 4 min read

An innovative assay permits researchers to screen for small molecule PARP inhibitors that trap the enzyme on DNA and selectively execute cancer cells.

Artist’s rendition of metastatic cancer cells with yellow nuclei and green cell bodies extending into blue tendrils.

While the Body Rests, Breast Cancer Spreads More Aggressively

Alejandra Manjarrez, PhD | Jun 23, 2022 | 4 min read

More cancer cells are shed from primary tumors when individuals are asleep than when they’re awake, according to observations in mouse models and a small cohort of breast cancer patients.

Bacteria in Tumors Promote Metastasis in Mice

Sophie Fessl, PhD | Apr 7, 2022 | 3 min read

Microbes living inside cancer cells may help them spread to distant sites by enhancing the cells’ resistance to mechanical stress, a study shows.

Technique Talk: Modeling the Complexity of Human Tumors in 3-D Cell Cultures

The Scientist’s Creative Services Team | 1 min read

In this workshop, learn how to make precision medicine a reality by modeling human cancers in 3-D organoid cultures for drug screening.

A photo of a triple-negative breast cancer cell

A Fasting-Mimicking Diet Thwarts Breast Cancer in Mice

Devin A. Reese, PhD | Mar 1, 2022 | 2 min read

Coupling a diet low in calories, sugar, and protein with existing cancer drugs treats triple-negative breast cancer in mice, and low blood glucose is associated with better cancer outcomes in human patients.

health care provider standing in front of gynecology stirrups holding swabs for Pap smear

DNA Methylation Could Predict Ovarian, Breast Cancers

Anna Napolitano, PhD | Feb 11, 2022 | 5 min read

A pair of new studies finds that analyzing material from a Pap smear can reveal tumor risk in distant parts of the body, potentially allowing early interventions.

Understanding Cancer Evolution Through the Lens of Single Cell Genomics

The Scientist’s Creative Services Team | 1 min read

Nicholas Navin and Lars Velten discuss sampling, sequencing, and tracing single cells to study how cancer cells adapt to various environments.

Scientific illustration of a migrating breast cancer cell.

Breast Cancer Cells Churn Out Cholesterol to Fuel Metastasis

Alejandra Manjarrez, PhD | Feb 4, 2022 | 4 min read

A study uncovers a novel connection between the biomolecule and cancer progression.

Salmonella (pink) invading a human epithelial cell (yellow)

Modified Salmonella Revs Immune Response, Combats Tumors in Mice

Natalia Mesa, PhD | Feb 3, 2022 | 5 min read

When coated with positively charged particles, the bacteria shuttled antigens out of tumors and activated the immune system, a study finds.

Cancer Vaccines: Raising a T Cell Army

Niki Spahich, PhD | 1 min read

Vaccines against various forms of cancer prime the immune system to attack.

brain scan showing uptake of tratuzumab into tumor (arrow)

Sound Waves Aid Brain Tumor Treatment

Ruth Williams | Oct 13, 2021 | 3 min read

In a small clinical study, focusing ultrasound beams on tumors in patients’ brains helped open the blood-brain barrier to facilitate drug delivery.

Mammary tumor organoids undergo a radical shape shift when treated with a microRNA.

Organoid Shape Identifies Potential Cancer Drugs

Roni Dengler, PhD | Aug 3, 2021 | 3 min read

An unusual drug screen takes advantage of “porcupine-like” structures of cancer cells in 3D organoids.

Homing Technology Delivers Therapy to Cancerous Bone

Roni Dengler, PhD | Jul 19, 2021 | 5 min read

A clever approach to modifying already existing cancer therapies may be a game changer for treating metastatic breast cancer.

José Baselga, cancer, research, oncology, AstraZeneca, breast cancer, drugs, therapeutics, obituary, dies

José Baselga, Renowned Oncologist, Dies at 61

Asher Jones | Mar 22, 2021 | 2 min read

The cancer researcher and executive vice president of AstraZeneca’s oncology research and development is well known for his role in the development of pivotal breast cancer therapies.