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Artist’s rendition of orange DNA coiled around a blue histone protein.
“Cryptic Transcription”: How Aging Cells Express Fragments of Genes
Aging cells with weakened gene regulation spuriously transcribe RNAs, but their impact on health and longevity still needs to be examined.
“Cryptic Transcription”: How Aging Cells Express Fragments of Genes
“Cryptic Transcription”: How Aging Cells Express Fragments of Genes

Aging cells with weakened gene regulation spuriously transcribe RNAs, but their impact on health and longevity still needs to be examined.

Aging cells with weakened gene regulation spuriously transcribe RNAs, but their impact on health and longevity still needs to be examined.

aging

mouse
hCINAP Protein Key to Cellular Senescence: Study
Patience Asanga | Mar 23, 2023 | 3 min read
The authors claim that by preventing the formation of senescent cells, the protein could delay aging, but experts are skeptical.
A 3D medical illustration of a human heart with a cardiogram in the foreground and a blue background that includes DNA helices.
Connecting the Complexities of Heart Failure and Aging
Deanna MacNeil, PhD | Feb 13, 2023 | 3 min read
Researchers learned how IGFBP7, a senescence signaling protein and biomarker, promotes cardiac remodeling and cellular aging.
Cellular Senescence: Why Do Cells Stop Dividing?
Cellular Senescence: Why Do Cells Stop Dividing?
Elina Kadriu | 4 min read
Senescent cells undergo major morphological and metabolic changes when at the end of their lifespan. 
A green and white fish swimming underwater
Rockfish Genes Hold Clues to Human Longevity
Natalia Mesa, PhD | Jan 12, 2023 | 3 min read
By analyzing the genomes of 23 remarkably long-lived fish species, a study found two metabolic pathways associated with longevity.
A younger-looking mouse next to an older-looking one
Epigenetic Manipulations Can Accelerate or Reverse Aging in Mice
Alejandra Manjarrez, PhD | Jan 12, 2023 | 4 min read
Repairing damaged DNA appears to drive aging by causing the loss of epigenetic information, but restoring that information reverses such effects, a study finds.
The fight against time
The Scientist Speaks - The Fight Against Time: Stem Cells and Healthy Aging 
The Scientist’s Creative Services Team | 2 min read
Tricking the body into mimicking a fasting state may hold the key to fighting age-related cognitive decline. 
Micrograph of kidney tissue from a mouse
Vesicles from Young Mice Alleviate Signs of Aging in Older Animals
Catherine Offord | Oct 19, 2022 | 4 min read
Mice that received the stem cell–derived treatment were less frail compared with controls, a study reports.
a false color transmission electron microscope image of a neuronal cell body, with lysosomes colored dark green
Scientists Uncover Major Pathway Cells Use to Mend Leaky Lysosomes
Holly Barker, PhD | Oct 6, 2022 | 3 min read
Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say.
A mole-rat poses in the grass 
The Scientist Speaks - Exploring the Secrets to Longevity and Cancer Resistance in Mole-Rats
The Scientist’s Creative Services Team | 1 min read
Vera Gorbunova discusses what naked and blind mole-rat cells reveal about aging and cancer resistance mechanisms. 
White mice in a clear plastic cage
Different Genes Influence Lifespan in Male and Female Mice
Natalia Mesa, PhD | Sep 29, 2022 | 3 min read
Researchers say there may be similar, human genes whose effects on lifespan vary by sex.
3D rendered images of three T cell
T Cells Ward Off Aging with Help from Their Friends
Natalia Mesa, PhD | Sep 16, 2022 | 5 min read
Immune cells deliver packages of telomeres to T cells, helping them retain their virus-fighting function over time, research suggests.
A person holding a section of his face and looking in to his brain through a magnifying glass stock illustration
Science Philosophy in a Flash - A Look at Aging Through Young Eyes 
Iris Kulbatski, PhD | 1 min read
Aimée Parker shares how her childlike curiosity and collaborative spirit motivate her scientific pursuits.
Woman holding a glass of water in one hand and pill in the other
Daily Multivitamin May Slow Cognitive Decline in Seniors
Andy Carstens | Sep 14, 2022 | 2 min read
Researchers caution that it’s too soon to recommend supplements based on the results of a new study.
ant with wings on white background
Secret to Reproductive Ants’ Longevity Revealed
Patience Asanga | Sep 2, 2022 | 3 min read
Researchers say they've figured out how some reproductive ants live up to 30 years—far longer than workers.
A Rising Star Launches Brain Power into Outer Space
Science Philosophy in a Flash - A Rising Star Launches Brain Power into Outer Space
Iris Kulbatski, PhD | 1 min read
Alysson Muotri shares how tapping into his inner creative spark fuels his pursuit of science.
LAKSAMEE CAVE
Clinton Cave Investigates How Brain Cells Communicate
Andy Carstens | Sep 1, 2022 | 3 min read
The Middlebury College neuroscientist explores enzymes that affect brain cell development and neurodegeneration.
Time Traveling Mini-Brains on a Mission to Conquer Space
Time Traveling Mini-Brains on a Mission to Conquer Space
Iris Kulbatski, PhD | Aug 11, 2022 | 4 min read
Alysson R. Muotri discusses his launch of brain organoids into outer space and how microgravity enriches our understanding of brain development and disease.
800x560-aug-31-2021
Aging and Cancer: A Complex Relationship
The Scientist’s Creative Services Team | 2 min read
An expert panel will discuss how aging affects cancer risk, development, and treatment practices.
An abstract stained-glass portrait of a woman with an image of an eye representing the brain
Through the Looking Glass: Aging, Inflammation, and Gut Rejuvenation
Iris Kulbatski, PhD | Aug 8, 2022 | 4 min read
Renewing the aging gut microbiome holds promise for preventing inflammatory brain and eye degeneration.
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